The Revolutionary Drug Delivery Liposome

By Gabrielle Lambert


Liposome is designed to deliver drugs very effectively. It is made as an artificial cell, and it is useful in medicine in many different ways. There are three basic types of liposomes; MLV means multilamillar vesicle, and SUV and LUV are unilamellar vesicles, small and large ones. They have very specific spherical shape and high drug delivery efficacy. They can be designed for oral use, or in form of lotions, creams or patches. You can also inhale them in form of dry spray or nasal spray, or take them intravenously.

There are so many fields where they can be used, for example in food industry, agriculture or cosmetology. They are highly efficient carriers of all types of enzymes and supplements, and thanks to the fact they are actually very similar to the real cells, they have very high biocompatibility, comparing to any other carrier. It lowers the chances for different side effects, as well as improving the diffusion and absorption of the particular drug.

This tiny capsule made of phospholipids is recognized as a real cell in a blood stream, and have the ability to find targeting areas. It could be very useful for all cancer treatments, especially tumors. Tumors have different membranes than other cells, and these bubbles are designed to penetrate those membranes and deliver particular drug inside the tumor.

In addition, they are capable to carry large pieces of DNA as well. In other forms of transfer, DNA gets damaged through various degrading processes, but this way it is protected from them. Capsules may have bi layered membranes, and they can carry positively, but also negatively charged molecules. Additionally, they can be both hydrophilic and lipophilic, or to have only one of those characteristics.

There are numerous effective anticancer drugs, but their therapeutic use is sometimes challenged by different issues like drug solubility and hydrolysis. This type of drug delivery can overcome some of these problems. Different formulations can retain particular drug in buffer. They have higher retention potential and prolonged circulation, compared to free drugs.

It is proven that different pills and capsules taken orally just lose their effectiveness due to gastric system and some other related problems. Thanks to that, the level of absorption is much lower than it should be. Liposomes are very useful for taking dietary and nutritional supplements, because they significantly improve the absorption of those nutrients, making them more effective.

Dietary and nutritional supplements can be carried within these small capsules to all targeting areas. Both lipophilic and hydrophilic nutritive supplements are effectively protected within those bubbles, and gastric system cannot harm them. Capsules ensure very high level of drug absorbtion, making those nutrients much more effective.

Nano liposomes are even smaller than those mentioned before, and have significantly higher efficacy. Of course, different factors affect the final quality, for example, the material used in process of production, the latest technology, size and some other conditions. The most important thing is to produce the adequate version for each particular purpose. In conclusion, liposome might change the drug industry very soon.




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