Lion's Mane Mushroom (Hericium erinaceus) and Nerve Regeneration

By Dr. Markho Rafael


The unique flavor of the gourmet mushroom Lion's Mane (Hericium erinaceus) is often compared to either lobster or shrimp. And modern science is now discovering that not only is it a culinary delicacy but it may also possess some unique medicinal properties, with its ability to stimulate nerve and myelin regeneration. (150, 151) In the book Mycelium Running, foremost American medicinal mushroom expert Paul Stamets suggests this may make Hericium erinaceus useful in a large number of neurological conditions, from multiple sclerosis and muscular dystrophy to Alzheimer's and dementia. (134)

In the wild, Lion's Mane Mushroom (Hericium erinaceus) grows on hardwood trees, especially oak, sycamore, maple, walnut and beech. It can be found throughout the temperate areas of the world, from North America and Europe to Japan and China.

"Erinacines" is the name of the medicinal compounds from Hericium erinaceus that are being researched for their neurological health benefits. They are small enough to pass through the blood brain barrier, which or course is a requirement in order to effect any healing on the myelin sheaths or neurons. (152, 153, 154)

Two Japanese patents exist relating to Hericium erinaceus extracts; one from the 1990's for an extraction process of these compounds yielding an extract known as "Nerve Growth Stimulant Factor." (150, 151) A more recent one from 2004 is for a water extract of Hericium erinaceus, also used for its nerve regenerating properties. (155)

In Traditional Chinese Medicine (TCM), Hericium erinaceus has historically been prescribed not only for neurological conditions but also for ailments of the digestive tract, in particular for cancers of the digestive organs, such stomach cancer and liver cancer.

Modern studies have affirmed the validity of this traditional application of Hericium erinaceus extract. One paper published in 1985 reported positive findings in the treatment of atrophic gastritis. Another from 1995 concluded that Hericium erinaceus had an ameliorating effect on hepatoma with an increased life expectancy for treated patients. (156)

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner.

Credit to Paul Stamets for research and source material.




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